Honorable Mention

VBridge: Connecting the Dots Between Features and Data to Explain Healthcare Models

Furui Cheng, Dongyu Liu, Fan Du, Yanna Lin, Alexandra Zytek, Haomin Li, Huamin Qu, Kalyan Veeramachaneni

View presentation: 2021-10-29T16:15:00Z GMT-0600 Change your timezone on the schedule page
Exemplar figure, described by caption below
The interface of VBridge facilitates clinicians’ understanding and interpretation of ML model predictions. The header menu allows clinicians to view prediction results, and to select a patient group for reference. The profile view and the timeline view show a summary of the target patient’s health records. The feature view shows feature-level explanations in a hierarchical display, linked to the temporal view where healthcare time series are visualized to provide context for feature-level explanations.

Machine learning (ML) is increasingly applied to Electronic Health Records (EHRs) to solve clinical prediction tasks. Although many ML models perform promisingly, issues with model transparency and interpretability limit their adoption in clinical practice. Directly using existing explainable ML techniques in clinical settings can be challenging. Through literature surveys and collaborations with six clinicians with an average of 17 years of clinical experience, we identified three key challenges, including clinicians' unfamiliarity with ML features, lack of contextual information, and the need for cohort-level evidence. Following an iterative design process, we further designed and developed VBridge, a visual analytics tool that seamlessly incorporates ML explanations into clinicians' decision-making workflow. The system includes a novel hierarchical display of contribution-based feature explanations and enriched interactions that connect the dots between ML features, explanations, and data. We demonstrated the effectiveness of VBridge through two case studies and expert interviews with four clinicians, showing that visually associating model explanations with patients' situational records can help clinicians better interpret and use model predictions when making clinician decisions. We further derived a list of design implications for developing future explainable ML tools to support clinical decision-making.